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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK1 All Species: 35.45
Human Site: S134 Identified Species: 65
UniProt: Q96SB4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SB4 NP_003128.3 655 74325 S134 L L K S V R N S D P N D P N R
Chimpanzee Pan troglodytes XP_518428 831 92792 S310 L L K S V R N S D P N D P N R
Rhesus Macaque Macaca mulatta XP_001116721 831 92803 S310 L L K S V R N S D P N D P N R
Dog Lupus familis XP_850330 823 92006 S302 L L K S V R N S D P N D P N R
Cat Felis silvestris
Mouse Mus musculus O70551 648 73070 S134 L L K S V R N S D P N D P N G
Rat Rattus norvegicus NP_001020897 655 73837 S134 L L K S V R N S D P N D P N G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516210 528 59280 V93 P E N I L L S V N E Q Y I R R
Chicken Gallus gallus XP_419265 754 84415 S225 L L K S V R N S D P N D P N K
Frog Xenopus laevis NP_001085122 605 68633 T134 L L R S V R N T D P N D P N R
Zebra Danio Brachydanio rerio NP_001074138 640 71523 T131 L L K A V R N T D Q N D P S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03563 1003 112508 N175 V N E N D H S N E D D E Q S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51567 427 49548
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 A212 L L Q R V N D A D N T K E D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 78.2 76.7 N.A. 91.4 91.4 N.A. 65.5 70.1 67.6 64.7 N.A. N.A. N.A. 23.1 N.A.
Protein Similarity: 100 78.6 78.5 77.6 N.A. 94.6 94 N.A. 70.3 77.3 78.1 76.1 N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 6.6 93.3 86.6 73.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 26.6 100 100 93.3 N.A. N.A. N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. 36 49.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 77 8 8 70 0 8 0 % D
% Glu: 0 8 8 0 0 0 0 0 8 8 0 8 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 62 0 0 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 77 77 0 0 8 8 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 8 0 8 70 8 8 8 70 0 0 62 0 % N
% Pro: 8 0 0 0 0 0 0 0 0 62 0 0 70 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 8 8 0 8 0 0 % Q
% Arg: 0 0 8 8 0 70 0 0 0 0 0 0 0 8 54 % R
% Ser: 0 0 0 62 0 0 16 54 0 0 0 0 0 16 8 % S
% Thr: 0 0 0 0 0 0 0 16 0 0 8 0 0 0 0 % T
% Val: 8 0 0 0 77 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _